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Mutation Information
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Mutation Site
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F61L |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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RT |
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Viral Reference
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K03455.1
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Literature Information
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PubMed PMID
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16723431
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Published Year
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2006 |
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Journal
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Nucleic acids research |
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Title
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Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H function. |
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Author
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Mandal D,Dash C,Le Grice SF,Prasad VR |
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Evidence
|
Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H functionWe reported previously that substitutions F61L, F61W, F61Y and F61A in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase affect strand displacement synthesis [T.
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