HBV Mutation Detail Information

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Mutation Information
Mutation Site F97L
Mutation Type Amino acid level
Gene/Protein/Region Type C
Literature Information
PubMed PMID 33879615
Published Year 2021
Journal Proceedings of the National Academy of Sciences of the United States of America
Title A pocket-factor-triggered conformational switch in the hepatitis B virus capsid.
Author Lecoq L,Wang S,Dujardin M,Zimmermann P,Schuster L,Fogeron ML,Briday M,Schledorn M,Wiegand T,Cole L,Montserret R,Bressanelli S,Meier BH,Nassal M,Böckmann A
Evidence To pinpoint the structural origin of the two conformations, we compared capsids from further Cp types (SI Appendix, Table S2), namely, from sevenfold phosphorylated P7-Cp183 (SI Appendix, Fig. S2) (11), the partial phosphorylation mimic Cp183-EEE (11), the immature secretion variant Cp183-F97L, CTD-less Cp149, T = 3-dominated Cp140 capsids, genotype-G capsids (44), and cell-free synthesized CF-Cp183 (45).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation