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Mutation Information
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Mutation Site
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F99V |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
PR |
Literature Information
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PubMed PMID
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31906562
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Published Year
|
2020 |
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Journal
|
Viruses |
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Title
|
HIV-1 Mutant Assembly, Processing and Infectivity Expresses Pol Independent of Gag. |
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Author
|
Yu FH,Huang KJ,Wang CT |
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Evidence
|
To clarify the impact of HIV-1 Pol containing a PR-RT fusion on virus assembly and processing, we created a G2AP-derived construct (designated G2AP/F99V) containing a mutation-blocking cleavage at PR-RT (Figure 6A).
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HIV Mutation Detail Information