|
Mutation Information
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Mutation Site
|
G129A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
11208474
|
|
Disease
|
HBV infection
|
|
Published Year
|
2000 |
|
Journal
|
Medical science monitor : international medical journal of experimental and clinical research |
|
Title
|
Analysis of HBs antigen negative variant of hepatitis B virus: unique substitutions, Glu129 to Asp and Gly145 to Ala in the surface antigen gene. |
|
Author
|
Koyanagi T,Nakamuta M,Sakai H,Sugimoto R,Enjoji M,Koto K,Iwamoto H,Kumazawa T,Mukaide M,Nawata H |
|
Evidence
|
However, the substitution of substitution glycine to alanine at position 129 introduce a putative glycosylation site (Asn-Gly-Thr), which may interfere with the antigenicity of HbsAg.
|
|
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HBV Mutation Detail Information