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Mutation Information
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Mutation Site
|
G140S |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
IN |
|
Genotype/Subtype
|
B |
|
Relevant Drug
|
INSTIs |
Literature Information
|
PubMed PMID
|
31591964
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2019 |
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Journal
|
eLife |
|
Title
|
Epistasis and entrenchment of drug resistance in HIV-1 subtype B. |
|
Author
|
Biswas A,Haldane A,Arnold E,Levy RM |
|
Evidence
|
Figure 6 shows the distribution of the change in Potts energy, (log likelihood) values for the DRMS N155H (panel A) and G140S (panel B) in HIV IN in different drug-experienced sequence backgrounds in the Stanford HIVDB along with the change in the specific backgrounds of NL4-3, HXB-2 and the subtype B consensus sequences.
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HIV Mutation Detail Information