HBV Mutation Detail Information

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Mutation Information

Mutation Site	G145A
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Genotype/Subtype	A

Literature Information

PubMed PMID	22967103
Published Year	2012
Journal	Journal of viral hepatitis
Title	Mutations associated with occult hepatitis B virus infection result in decreased surface antigen expression in vitro.
Author	Martin CM,Welge JA,Rouster SD,Shata MT,Sherman KE,Blackard JT
Evidence	Site-directed mutagenesis was then utilized to introduce three genotype A mutations - M103I, K122R and G145A - associated with Occult hepatitis B in vivo, alone and in combination, into the wild-type HBsAg vectors.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation