|
Mutation Information
|
Mutation Site
|
G145A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
Ba |
|
Immune Escape
|
Y |
Literature Information
|
PubMed PMID
|
32978866
|
|
Disease
|
HBV infection
|
|
Published Year
|
2021 |
|
Journal
|
Hepatology research : the official journal of the Japan Society of Hepatology |
|
Title
|
Case of hepatitis B virus reactivation after ibrutinib therapy in which the patient remained negative for hepatitis B surface antigens throughout the clinical course. |
|
Author
|
Tsuruya K,Anzai K,Shioyama S,Ito A,Arase Y,Hirose S,Tanaka Y,Suzuki H,Kagawa T |
|
Evidence
|
Interestingly, the patient remained negative for HBsAg throughout the clinical course owing to triple HBsAg escape mutations: Q101K, M133L, and G145A.
|
|
|
HBV Mutation Detail Information