|
Mutation Information
|
Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
AY220698
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
16419112
|
|
Disease
|
Acute hepatitis B
|
|
Published Year
|
2006 |
|
Journal
|
Journal of medical virology |
|
Title
|
Fatal liver failure with the emergence of hepatitis B surface antigen variants with multiple stop mutations after discontinuation of lamivudine therapy. |
|
Author
|
Zhang JM,Wang XY,Huang YX,Yin YK,Guan S,Xu Y,Roggendorf M,Lu M |
|
Evidence
|
Sequencing of HBV isolates revealed that mutations including G145R and stop codons occurred within the HBsAg coding region.
|
|
|
HBV Mutation Detail Information