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Mutation Information
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Mutation Site
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G145R |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
S |
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Combined Mutation
|
s.G145R+s.T126S;s.G145R+s.D144A |
|
Country
|
Thailand |
Literature Information
|
PubMed PMID
|
16553556
|
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Published Year
|
2006 |
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Journal
|
Viral immunology |
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Title
|
HBsAg diagnostic kits in the detection of hepatitis B virus mutation within "a" determinant. |
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Author
|
Louisirirotchanakul S,Kanoksinsombat C,O'Charoen R,Fongsatikul L,Puapairoj C,Lulitanond V,Appassakij H,Promwong C,Wasi C |
|
Evidence
|
Interestingly, any commercial kits with monoclonal antibody capture and polyclonal antibody detection (mono/poly), but not mono/mono Ab capture and detection, could pick up the common HBsAg Gly145Arg mutant either solely or in combination with other mutations within the "a" determinant.
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