|
Mutation Information
|
Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
Literature Information
|
PubMed PMID
|
19998495
|
|
Published Year
|
2009 |
|
Journal
|
World journal of gastroenterology |
|
Title
|
Clinical relevance and public health significance of hepatitis B virus genomic variations. |
|
Author
|
Cao GW |
|
Evidence
|
HBV mutations in the S genes, especially amino acids substitution at position 145 (G145R), are associated with immune escape, whereas mutations in the PreS or S genes which impair HBsAg secretion could present a risk to blood safety.
|
|
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HBV Mutation Detail Information