HBV Mutation Detail Information

> G145R Search Result

Mutation Information

Mutation Site	G145R
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Genotype/Subtype	A
Immune Escape	Y
Country	Spain

Literature Information

PubMed PMID	22666402
Disease	Chronic hepatitis B
Published Year	2012
Journal	PloS one
Title	Ultra-deep pyrosequencing detects conserved genomic sites and quantifies linkage of drug-resistant amino acid changes in the hepatitis B virus genome.
Author	Rodriguez-Frías F,Tabernero D,Quer J,Esteban JI,Ortega I,Domingo E,Cubero M,Camós S,Ferrer-Costa C,Sánchez A,Jardí R,Schaper M,Homs M,Garcia-Cehic D,Guardia J,Esteban R,Buti M
Evidence	In the “a determinant”, only substitution sG145R (0.11%), the main HBsAg immune escape variant [26], was present at >0.1%.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation