|
Mutation Information
|
Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
A;C;D |
|
Country
|
Italy |
Literature Information
|
PubMed PMID
|
23296324
|
|
Clinical information
|
Yes
|
|
Disease
|
HBV infection
|
|
Published Year
|
2013 |
|
Journal
|
Human vaccines & immunotherapeutics |
|
Title
|
Epidemiology of HBV S-gene mutants in the Liguria Region, Italy: Implications for surveillance and detection of new escape variants. |
|
Author
|
Sticchi L,Caligiuri P,Cacciani R,Alicino C,Bruzzone B |
|
Evidence
|
The emergence of these mutants, at least the G145R, has already been addressed as a public health concern because of its capability of escaping the immune system.
|
|
|
HBV Mutation Detail Information