HBV Mutation Detail Information

> G145R Search Result

Mutation Information

Mutation Site	G145R
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Genotype/Subtype	D
Viral Reference	X02496
Immune Escape	Y
Country	Greece

Literature Information

PubMed PMID	23773581
Disease	Fulminant hepatitis B
Published Year	2013
Journal	Transplant infectious disease : an official journal of the Transplantation Society
Title	Renal transplantation from hepatitis B surface antigen (HBsAg)-positive donors to HBsAg-negative recipients: a case of post-transplant fulminant hepatitis associated with an extensively mutated hepatitis B virus strain and review of the current literature.
Author	Magiorkinis E,Paraskevis D,Pavlopoulou ID,Kantzanou M,Haida C,Hatzakis A,Boletis IN
Evidence	RESULTS: Molecular analysis revealed multiple mutations in various open reading frames of HBV, the most important being the G145R escape mutation and a frameshift mutation-insertion (1838insA) within the pre-C/C reading frame.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation