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Mutation Information
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Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
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Genotype/Subtype
|
F |
|
Relevant Drug
|
entecavir (ETV) |
|
Country
|
Germany |
Literature Information
|
PubMed PMID
|
30079137
|
|
Disease
|
Acute hepatitis B
|
|
Published Year
|
2018 |
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Journal
|
World journal of hepatology |
|
Title
|
Hepatitis B virus subgenotype F3 reactivation with vaccine escape mutations: A case report and review of the literature. |
|
Author
|
Schlabe S,van Bremen K,Aldabbagh S,Glebe D,Bremer CM,Marsen T,Mellin W,Cristanziano VD,Eis-Hübinger AM,Spengler U |
|
Evidence
|
We examined the effects of two closely related CpAMs, HAP12 and HAP13, which differ by a single atom but have drastically different antiviral activities, on the assembly of wild-type Cp and three T109 mutants (T109M, T109I, and T109S) that display a range of resistances.
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HBV Mutation Detail Information