|
Mutation Information
|
Mutation Site
|
G149R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PreS2 |
|
Country
|
Taiwan;China |
Literature Information
|
PubMed PMID
|
12974898
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2003 |
|
Journal
|
Journal of gastroenterology and hepatology |
|
Title
|
Identification of a novel pre-S2 mutation in a subgroup of chronic carriers with spontaneous clearance of hepatitis B virus surface antigen. |
|
Author
|
Yeh CT,Chang MH,Lai HY,Chang ML,Chu CM,Liaw YF |
|
Evidence
|
Site-directed mutagenesis experiments showed that secretion of HBsAg was not defective in the pre-S2 G149R mutant.
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HBV Mutation Detail Information