|
Mutation Information
|
Mutation Site
|
G163R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Combined Mutation
|
in.G163R+in.S153Y |
|
Genotype/Subtype
|
AE;B |
|
Viral Reference
|
AF324493.2;
AF096341.1 |
|
Relevant Drug
|
cabotegravir (CAB);raltegravir (RAL);elvitegravir (EVG);bictegravir (BIC);dolutegravir (DTG) |
|
Country
|
Canada |
Literature Information
|
PubMed PMID
|
30119633
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
Retrovirology |
|
Title
|
Selective resistance profiles emerging in patient-derived clinical isolates with cabotegravir, bictegravir, dolutegravir, and elvitegravir. |
|
Author
|
Oliveira M,Ibanescu RI,Anstett K,Mésplède T,Routy JP,Robbins MA,Brenner BG,Montreal Primary HIV (PHI) Cohort Study Group. |
|
Evidence
|
Two other variants, 14947 and 6343, acquired R263K/S153A and S153Y/G163R variants.
|
|
|
HIV Mutation Detail Information