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Mutation Information
|
Mutation Site
|
G163R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Combined Mutation
|
in.G163R+in.N155H;in.G163R+in.N155H+in.V151I+in.L74I;in.G163R+in.Y143R+in.T97A+in.L74M;in.G163R+in.Q148R+in.Q148H;in.G163R+in.T79A;in.G163R+in.T97A;in.G163R+in.N155H+in.T97A;in.G163R+in.E157Q+in.N155H+in.V151I |
|
Relevant Drug
|
INSTIs |
|
Country
|
Argentina |
Literature Information
|
PubMed PMID
|
31037930
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2019 |
|
Journal
|
Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia |
|
Title
|
Resistance to HIV integrase strand transfer inhibitors in Argentina: first interim survey. |
|
Author
|
Cecchini DM,Castillo S,Copertari G,Lacal V,Rodriguez CG,Cassetti I |
|
Evidence
|
Predominant combinations of mutations were 140A/S + Q148H/R and N155H + G163K/R.
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