HBV Mutation Detail Information

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Mutation Information

Mutation Site	G1764A
Mutation Type	Nucleotide level
Gene/Protein/Region Type	BCP
Genotype/Subtype	B;C
Country	Japan

Literature Information

PubMed PMID	11124839
Disease	Chronic hepatitis B
Published Year	2001
Journal	Hepatology (Baltimore, Md.)
Title	A case-control study for clinical and molecular biological differences between hepatitis B viruses of genotypes B and C. Japan HBV Genotype Research Group.
Author	Orito E,Mizokami M,Sakugawa H,Michitaka K,Ishikawa K,Ichida T,Okanoue T,Yotsuyanagi H,Iino S
Evidence	The double mutation in the basic core promoter (A-to-T at nt 1762 and G-to-A at nt 1764), however, was significantly more frequent in genotype C than B patients (58% vs. 16%, P <.01), and it did not correlate with anti-HBe or HBeAg.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation