|
Mutation Information
|
Mutation Site
|
G1764A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
bcp.G1764A+bcp.A1762T |
|
Genotype/Subtype
|
B;C |
|
Immune Escape
|
Y |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
15256984
|
|
Disease
|
HBV associated polyarteritis nodosa
|
|
Published Year
|
2004 |
|
Journal
|
European journal of gastroenterology & hepatology |
|
Title
|
Polyarteritis nodosa associated with hepatitis B virus infection. The role of antiviral treatment and mutations in the hepatitis B virus genome. |
|
Author
|
Janssen HL,van Zonneveld M,van Nunen AB,Niesters HG,Schalm SW,de Man RA |
|
Evidence
|
In one patient a stop codon in the pre-core region and a double mutation A1762T-G1764A were found during antiviral therapy.
|
|
|