|
Mutation Information
|
Mutation Site
|
G1764A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
bcp.G1764A+bcp.A1762T |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
17464459
|
|
Clinical information
|
Yes
|
|
Disease
|
Occult HBV infection;
Hepatocellular carcinoma
|
|
Published Year
|
2007 |
|
Journal
|
Journal of gastroenterology |
|
Title
|
A weak association between occult HBV infection and non-B non-C hepatocellular carcinoma in Japan. |
|
Author
|
Kusakabe A,Tanaka Y,Orito E,Sugauchi F,Kurbanov F,Sakamoto T,Shinkai N,Hirashima N,Hasegawa I,Ohno T,Ueda R,Mizokami M |
|
Evidence
|
In the NBNC-HCC group, the determined nucleotide sequences of the enhancer II/core promoter/precore/core region did not contain any HCC-associated mutations, whereas 25 of 30 patients in the HBV-HCC group carried strains with C1653T, T1753V, and/or A1762T/G1764A mutations.
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HBV Mutation Detail Information