HBV Mutation Detail Information

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Mutation Information

Mutation Site	G1764A
Mutation Type	Nucleotide level
Gene/Protein/Region Type	BCP
Genotype/Subtype	C
Country	China

Literature Information

PubMed PMID	21503912
Disease	Acute on chronic liver failure
Published Year	2011
Journal	Journal of medical virology
Title	T1846 and A/G1913 are associated with acute on chronic liver failure in patients infected with hepatitis B virus genotypes B and C.
Author	Yan T,Li K,Li F,Su H,Mu J,Tong S,Patel M,Xia J,Wands JR,Wang H
Evidence	Therefore, the A1846T mutation seems to be similar to core promoter mutations (T1753C, A1762T, G1764A, C1766T, T1768A) and G1896A precore mutation in association with age‐dependent disease progression (LC and HCC) as well as with severe liver diseases (fulminant hepatitis and ACLF).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation