HBV Mutation Detail Information

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Mutation Information

Mutation Site	G1764A
Mutation Type	Nucleotide level
Gene/Protein/Region Type	BCP
Combined Mutation	bcp.G1764A+bcp.A1762T
Genotype/Subtype	C
Country	Korean

Literature Information

PubMed PMID	31402915
Disease	HBV associated liver disease
Published Year	2019
Journal	Frontiers in immunology
Title	rt269I Type of Hepatitis B Virus (HBV) Leads to HBV e Antigen Negative Infections and Liver Disease Progression via Mitochondrial Stress Mediated Type I Interferon Production in Chronic Patients With Genotype C Infections.
Author	Lee SY,Choi YM,Oh SJ,Yang SB,Lee J,Choe WH,Kook YH,Kim BJ
Evidence	Of the various HBV mutations, G1896A mutations on the pre-core region (preC mutation) and A1762T/G1764A double mutations on the basal core promoter (BCP) lead to HBeAg negative infection that are significantly related to liver disease progression (23).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation