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HBV Mutation Detail Information

> G1862T Search Result


Mutation Information
Mutation Site G1862T
Mutation Type Nucleotide level
Gene/Protein/Region Type PreC
Combined Mutation prec.G1862T+prec.G1899A
Nucleotide_Mutation V17F
Literature Information
PubMed PMID 16378961
Published Year 2006
Journal Journal of virology
Title Point mutations upstream of hepatitis B virus core gene affect DNA replication at the step of core protein expression.
Author Guarnieri M,Kim KH,Bang G,Li J,Zhou Y,Tang X,Wands J,Tong S
Evidence This replication defect was associated with reduced expression of core protein and could be overcome by a G1899A covariation, or by nonsense or frameshift mutation in the precore region. All these mutations antagonized the G1862T mutation on core protein expression.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation