|
Mutation Information
|
Mutation Site
|
G1862T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Nucleotide_Mutation
|
V17F |
|
Genotype/Subtype
|
D |
Literature Information
|
PubMed PMID
|
18201182
|
|
Published Year
|
2008 |
|
Journal
|
Hepatology research : the official journal of the Japan Society of Hepatology |
|
Title
|
A valine to phenylalanine mutation in the precore region of hepatitis B virus causes intracellular retention and impaired secretion of HBe-antigen. |
|
Author
|
Chen CY,Crowther C,Kew MC,Kramvis A |
|
Evidence
|
The formation of aggresomes, as a result of the G1862T mutation, may play a contributory role in HBV-induced liver disease.
|
|
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HBV Mutation Detail Information