|
Mutation Information
|
Mutation Site
|
G1891A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Nucleotide_Mutation
|
W26* |
Literature Information
|
PubMed PMID
|
16549970
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2006 |
|
Journal
|
AIDS (London, England) |
|
Title
|
Characteristics of drug resistant HBV in an international collaborative study of HIV-HBV-infected individuals on extended lamivudine therapy. |
|
Author
|
Matthews GV,Bartholomeusz A,Locarnini S,Ayres A,Sasaduesz J,Seaberg E,Cooper DA,Lewin S,Dore GJ,Thio CL |
|
Evidence
|
Two further patients had pre-core mutations that result in truncations of the pre-core protein including one genotype A virus truncated at G1891A (W26 stop) and one with a 1-base pair deletion after 1839, resulting in a frame shift.
|
|
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HBV Mutation Detail Information