|
Mutation Information
|
Mutation Site
|
G1896A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Genotype/Subtype
|
B;C |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
11124839
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2001 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
A case-control study for clinical and molecular biological differences between hepatitis B viruses of genotypes B and C. Japan HBV Genotype Research Group. |
|
Author
|
Orito E,Mizokami M,Sakugawa H,Michitaka K,Ishikawa K,Ichida T,Okanoue T,Yotsuyanagi H,Iino S |
|
Evidence
|
The predominance of mutants with G-to-A mutation at nucleotide (nt) 1896 in the precore region (A1896) over the wild-type was comparable between genotype B and C patients (60% and 62%, respectively), and it correlated with anti-HBe.
|
|
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HBV Mutation Detail Information