|
Mutation Information
|
Mutation Site
|
G1896A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Combined Mutation
|
prec.G1896A+bcp.G1764A+bcp.A1762T |
Literature Information
|
PubMed PMID
|
15918203
|
|
Disease
|
HBV associated liver disease
|
|
Published Year
|
2005 |
|
Journal
|
World journal of gastroenterology |
|
Title
|
High level of hepatitis B virus DNA after HBeAg-to-anti-HBe seroconversion is related to coexistence of mutations in its precore and basal core promoter. |
|
Author
|
Peng XM,Huang GM,Li JG,Huang YS,Mei YY,Gao ZL |
|
Evidence
|
The coexistence of G1896A mutation and A1762T/G1764A mutations is very common, and responsible for the major cases with high level of HBV DNA in serum and progressive liver diseases after HBeAg-to-anti-HBe seroconversion.
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