|
Mutation Information
|
Mutation Site
|
G1896A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Combined Mutation
|
prec.G1896A+c promoter.G1764A+c promoter.A1762T |
|
Genotype/Subtype
|
D |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Italy |
Literature Information
|
PubMed PMID
|
17652045
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2007 |
|
Journal
|
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver |
|
Title
|
Sequential treatment with lamivudine and alpha-interferon in anti-HBe-positive chronic hepatitis B patients: a pilot study. |
|
Author
|
Niro GA,Fontana R,Gioffreda D,Fiorella S,Accadia L,Iacobellis A,Caruso N,Conoscitore P,Andriulli A |
|
Evidence
|
Triple promoter mutations at nucleotides 1762-1764-1896 prevailed in non-responders (60%) as compared to responders (22%).
|
|
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HBV Mutation Detail Information