|
Mutation Information
|
Mutation Site
|
G1896A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Genotype/Subtype
|
B;C;D;I |
Literature Information
|
PubMed PMID
|
32283837
|
|
Published Year
|
2020 |
|
Journal
|
Viruses |
|
Title
|
In silico Analysis of Genetic Diversity of Human Hepatitis B Virus in Southeast Asia, Australia and New Zealand. |
|
Author
|
Phan NMH,Faddy H,Flower R,Spann K,Roulis E |
|
Evidence
|
Mutations within the PC region acquired after HBeAg seroconversion (c.1896G>A and p.P130T) can lead to defective HBV replication, decreased or lost secretion of HBeAg, HBeAg-negative CHB and even HCC with poorer prognosis.
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HBV Mutation Detail Information