HBV Mutation Detail Information

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Mutation Information

Mutation Site	G1896A
Mutation Type	Nucleotide level
Gene/Protein/Region Type	PreC
Nucleotide_Mutation	W28*
Genotype/Subtype	C

Literature Information

PubMed PMID	33803998
Published Year	2021
Journal	Microorganisms
Title	rt269I Type of Hepatitis B Virus (HBV) Polymerase versus rt269L Is More Prone to Mutations within HBV Genome in Chronic Patients Infected with Genotype C2: Evidence from Analysis of Full HBV Genotype C2 Genome.
Author	Jeong H,Kim DH,Choi YM,Choi H,Kim D,Kim BJ
Evidence	The preC-W28Stop, known as a preC mutation at 1896 nt, leads to premature termination of HBeAg, resulting in HBeAg-negative infection in chronic patients with its mutation, of which the frequency was significantly higher in rt269I strains than in rt269L strains (q < 0.001).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation