HBV Mutation Detail Information

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Mutation Information

Mutation Site	G1896A
Mutation Type	Nucleotide level
Gene/Protein/Region Type	PreC
Country	Greek

Literature Information

PubMed PMID	9751010
Disease	Chronic hepatitis B
Published Year	1998
Journal	Journal of viral hepatitis
Title	Incidence and clinical significance of hepatitis B virus precore gene translation initiation mutations in e antigen-negative patients.
Author	Laras A,Koskinas J,Avgidis K,Hadziyannis SJ
Evidence	These data show that a significant proportion of HBeAg-negative patients who already harbour the 1896 stop codon mutation may subsequently develop precore translation initiation mutations, which appear to be associated with enhanced HBV replication and severe liver disease.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation