|
Mutation Information
|
Mutation Site
|
G1897A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Combined Mutation
|
prec.G1897A+prec.G1896A |
Literature Information
|
PubMed PMID
|
11778699
|
|
Disease
|
HBV associated liver disease
|
|
Published Year
|
2001 |
|
Journal
|
Virus genes |
|
Title
|
Base-pair alterations in the epsilon-lower stem due to a novel double substitution in the precore gene of HBV-e negative variant were recovered by secondary mutations. |
|
Author
|
Parvez MK,Thakur V,Kazim SN,Guptan RC,Hasnain SE,Sarin SK |
|
Evidence
|
The HBe negative phenotype, a natural precore mutant (G1896A/G1897A) of HBV with aborted HBeAg expression is known to cause chronic hepatitis.
|
|
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HBV Mutation Detail Information