|
Mutation Information
|
Mutation Site
|
G1899A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Combined Mutation
|
prec.G1862T+prec.G1899A |
|
Nucleotide_Mutation
|
G29D |
Literature Information
|
PubMed PMID
|
16378961
|
|
Published Year
|
2006 |
|
Journal
|
Journal of virology |
|
Title
|
Point mutations upstream of hepatitis B virus core gene affect DNA replication at the step of core protein expression. |
|
Author
|
Guarnieri M,Kim KH,Bang G,Li J,Zhou Y,Tang X,Wands J,Tong S |
|
Evidence
|
This replication defect was associated with reduced expression of core protein and could be overcome by a G1899A covariation, or by nonsense or frameshift mutation in the precore region.
|
|
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HBV Mutation Detail Information