HBV Mutation Detail Information

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Mutation Information

Mutation Site	G1899A
Mutation Type	Nucleotide level
Gene/Protein/Region Type	PreC
Combined Mutation	prec.G1899A+prec.G1896A
Country	Brazil

Literature Information

PubMed PMID	28902288
Disease	Chronic hepatitis B
Published Year	2017
Journal	Memorias do Instituto Oswaldo Cruz
Title	Basal core promoter and precore mutations among hepatitis B virus circulating in Brazil and its association with severe forms of hepatic diseases.
Author	Chachá SGF,Gomes-Gouvêa MS,Malta FM,Ferreira SDC,Villanova MG,Souza FF,Teixeira AC,Passos ADDC,Pinho JRR,Martinelli ALC
Evidence	Among the 129 patients in whom the HBV PC region was analysed, a high frequency of HBV strains with G1896A mutation (53/129, 41%) was detected, alone or in G1896A/G1899A double mutation, particularly in the subgroup with HBeAg-negative chronic hepatitis (39/85, 45.9%) (p = 0.03).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation