|
Mutation Information
|
Mutation Site
|
G1899A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Combined Mutation
|
prec.G1899A+prec.G1896A |
|
Country
|
Germany |
Literature Information
|
PubMed PMID
|
33055418
|
|
Disease
|
HBV infection
|
|
Published Year
|
2020 |
|
Journal
|
JCI insight |
|
Title
|
Quadruple mutation GCAC1809-1812TTCT acts as a biomarker in healthy European HBV carriers. |
|
Author
|
Peiffer KH,Spengler C,Basic M,Jiang B,Kuhnhenn L,Obermann W,Zahn T,Glitscher M,Loglio A,Facchetti F,Carra G,Kubesch A,Vermehren J,Knop V,Graf C,Dietz J,Finkelmeier F,Herrmann E,Trebicka J,Grünweller A,Zeuzem S,Sarrazin C,Lampertico P,Hildt E |
|
Evidence
|
The specificity of the blot was proven by using an additional genome containing the precore double mutation G1896A/G1899A, which was used as an additional HBeAg negative control, and by using an HBeAg positive WT genome as a positive control (Figure 3A).
|
|
|
HBV Mutation Detail Information