|
Mutation Information
|
Mutation Site
|
G190S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.K103N+rt.G190S;rt.Y181C+rt.G190S |
|
Genotype/Subtype
|
A |
|
Relevant Drug
|
efavirenz (EFV);nevirapine (NPV) |
|
Country
|
Russia |
Literature Information
|
PubMed PMID
|
25259833
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2014 |
|
Journal
|
AIDS (London, England) |
|
Title
|
A uniquely prevalent nonnucleoside reverse transcriptase inhibitor resistance mutation in Russian subtype A HIV-1 viruses. |
|
Author
|
Kolomeets AN,Varghese V,Lemey P,Bobkova MR,Shafer RW |
|
Evidence
|
Therefore, G190S results from a single G→A transition: G (GGC) → S (AGC) almost exclusively in subtype AFSU viruses.
|
|
|
HIV Mutation Detail Information