|
Mutation Information
|
Mutation Site
|
G1986A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Genotype/Subtype
|
C |
|
Country
|
Korean |
Literature Information
|
PubMed PMID
|
31402915
|
|
Disease
|
HBV associated liver disease
|
|
Published Year
|
2019 |
|
Journal
|
Frontiers in immunology |
|
Title
|
rt269I Type of Hepatitis B Virus (HBV) Leads to HBV e Antigen Negative Infections and Liver Disease Progression via Mitochondrial Stress Mediated Type I Interferon Production in Chronic Patients With Genotype C Infections. |
|
Author
|
Lee SY,Choi YM,Oh SJ,Yang SB,Lee J,Choe WH,Kook YH,Kim BJ |
|
Evidence
|
In addition, the rate of G1986A preC mutation was significant higher in patients with rt269I (49.61%) than those with rt269L (28.83%, p < 0.01).
|
|
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HBV Mutation Detail Information