|
Mutation Information
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Mutation Site
|
G48A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Vif |
Literature Information
|
PubMed PMID
|
32665270
|
|
Published Year
|
2020 |
|
Journal
|
mBio |
|
Title
|
Convergent Evolution of HLA-C Downmodulation in HIV-1 and HIV-2. |
|
Author
|
Hopfensperger K,Richard J,Stürzel CM,Bibollet-Ruche F,Apps R,Leoz M,Plantier JC,Hahn BH,Finzi A,Kirchhoff F,Sauter D |
|
Evidence
|
The respective 7312A constructs harboring P16A, G48A, HC/LS, HCCH/LSSL, or SLQ/AAA vif mutations were generated using overlap extension PCR and inserted into the NL4-3 backbone via XmaI/EcoRI.
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HIV Mutation Detail Information