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Mutation Information
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Mutation Site
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G89V |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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CA |
Literature Information
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PubMed PMID
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33758083
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Published Year
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2021 |
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Journal
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mBio |
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Title
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Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner. |
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Author
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Zhong Z,Ning J,Boggs EA,Jang S,Wallace C,Telmer C,Bruchez MP,Ahn J,Engelman AN,Zhang P,Watkins SC,Ambrose Z |
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Evidence
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Because G89V HIV-1 is restricted by CPSF6-358 and thus can still bind CPSF6, we expected that this virus would induce CPSF6-GFP puncta that would not increase in number in the presence of CsA, which is what was observed (Fig.
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HIV Mutation Detail Information