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Mutation Information
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Mutation Site
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G99A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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X |
Literature Information
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PubMed PMID
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11287420
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Published Year
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2001 |
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Journal
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The Journal of biological chemistry |
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Title
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Interaction of the hepatitis B virus X protein with the Crm1-dependent nuclear export pathway. |
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Author
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Forgues M,Marrogi AJ,Spillare EA,Wu CG,Yang Q,Yoshida M,Wang XW |
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Evidence
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Percentages of cells with nuclear staining of NFκB that are positive for HBx are shown B. C, a luciferase reporter containing 4 NFκB responsive elements was transfected with HBx or an HBx mutant (HBxNESM, L98A, G99A, L100A) into a telomerase-immortalized human fibroblast line (NHF-hTERT) or a hepatocellular carcinoma cell line (Hep3B).
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HBV Mutation Detail Information