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Mutation Information
|
Mutation Site
|
H141F |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
BMRF1 |
|
Viral Reference
|
V01555.2
|
Literature Information
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PubMed PMID
|
19801550
|
|
Published Year
|
2009 |
|
Journal
|
The Journal of biological chemistry |
|
Title
|
Crystal structure of epstein-barr virus DNA polymerase processivity factor BMRF1. |
|
Author
|
Murayama K,Nakayama S,Kato-Murayama M,Akasaka R,Ohbayashi N,Kamewari-Hayami Y,Terada T,Shirouzu M,Tsurumi T,Yokoyama S |
|
Evidence
|
Although the R87E and H141F mutants of BMRF1-ΔC exhibited dramatically reduced polymerase processivity, they were still able to bind DNA and to dimerize.
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EBV Mutation Detail Information