|
Mutation Information
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Mutation Site
|
H18L |
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Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Gp125 |
Literature Information
|
PubMed PMID
|
33669351
|
|
Published Year
|
2021 |
|
Journal
|
International journal of molecular sciences |
|
Title
|
Computational Modulation of the V3 Region of Glycoprotein gp125 of HIV-2. |
|
Author
|
Serra PA,Taveira N,Guedes RC |
|
Evidence
|
The H18L variant replaced a basic residue with a hydrophobic residue and leads to the loss of the aromatic moiety which abrogated any possibility of establishment of pi-pi interactions within the V3 environment.
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HIV Mutation Detail Information