|
Mutation Information
|
Mutation Site
|
H51Y |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Relevant Drug
|
INSTIs |
Literature Information
|
PubMed PMID
|
27130466
|
|
Published Year
|
2016 |
|
Journal
|
Retrovirology |
|
Title
|
Effect on HIV-1 viral replication capacity of DTG-resistance mutations in NRTI/NNRTI resistant viruses. |
|
Author
|
Pham HT,Mesplède T,Wainberg MA |
|
Evidence
|
In-vitro-selected R263K was associated with impaired viral replication capacity, DNA integration, and integrase strand-transfer activity, especially when accompanied by the secondary mutation H51Y.
|
|
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HIV Mutation Detail Information