|
Mutation Information
|
Mutation Site
|
I120V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
CA |
|
Genotype/Subtype
|
C |
Literature Information
|
PubMed PMID
|
33836787
|
|
Published Year
|
2021 |
|
Journal
|
Retrovirology |
|
Title
|
A single G10T polymorphism in HIV-1 subtype C Gag-SP1 regulates sensitivity to maturation inhibitors. |
|
Author
|
Ghimire D,Kc Y,Timilsina U,Goel K,Nitz TJ,Wild CT,Gaur R |
|
Evidence
|
While the SP1:A1V mutant was resistant to the MIs, the CA:I120V mutant displayed partial resistance and a MI-dependent phenotype.
|
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HIV Mutation Detail Information