HBV Mutation Detail Information

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Mutation Information

Mutation Site	I126A
Mutation Type	Amino acid level
Gene/Protein/Region Type	C

Literature Information

PubMed PMID	26136564
Published Year	2015
Journal	Journal of virology
Title	An Aptamer against the Matrix Binding Domain on the Hepatitis B Virus Capsid Impairs Virion Formation.
Author	Orabi A,Bieringer M,Geerlof A,Bruss V
Evidence	A small domain (matrix domain [MD]) in the large surface protein L and a narrow region (matrix binding domain [MBD]) including isoleucine 126 on the capsid surface have been mapped, in which point mutations such as core I126A specifically blocked nucleocapsid envelopment.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation