|
Mutation Information
|
Mutation Site
|
I126N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
Literature Information
|
PubMed PMID
|
10535488
|
|
Disease
|
Chronic hepatitis B;
Hepatocellular carcinoma
|
|
Published Year
|
1999 |
|
Journal
|
Journal of gastroenterology |
|
Title
|
Detection of pre-S/S gene mutants in chronic hepatitis B carriers with concurrent hepatitis B surface antibody and hepatitis B surface antigen. |
|
Author
|
Wang YM,Ng WC,Lo SK |
|
Evidence
|
One of the HBV carriers with anti-HBs (group A) and an HCC patient with anti-HBs (group B) had point mutations in the a determinant, resulting in conversion from Ile-126 of wild-type to Asn-126.
|
|
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HBV Mutation Detail Information