|
Mutation Information
|
Mutation Site
|
I126S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
28373061
|
|
Clinical information
|
Yes
|
|
Disease
|
Liver cirrhosis;
Hepatocellular carcinoma
|
|
Published Year
|
2017 |
|
Journal
|
Virus research |
|
Title
|
Sequence analysis and functional characterization of full-length hepatitis B virus genomes from Korean cirrhotic patients with or without liver cancer. |
|
Author
|
Zhou H,Gewaily D,Ahn SH,Preskill C,Wang Y,Zong L,Zhang J,Han KH,Wands J,Li J,Tong S |
|
Evidence
|
The P120T, I126S, and R160G mutations did not affect intracellular HBsAg level, although R160G slightly reduced extracellular HBsAg (Fig. 6B).
|
|
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HBV Mutation Detail Information