HBV Mutation Detail Information

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Mutation Information

Mutation Site	I169T
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	entecavir (ETV);lamivudine (LAM)

Literature Information

PubMed PMID	22505793
Published Year	2011
Journal	International journal of current chemistry
Title	Hepatitis B Virus genotypic differences map structurally close to NRTI resistance hot spots.
Author	Michailidis E,Singh K,Kirby KA,Hachiya A,Yoo W,Hong SP,Kim SO,Folk WR,Sarafianos SG
Evidence	Mutation of this residue to a threonine (I169T) causes resistance to ETV and LVD (Table 1).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation