|
Mutation Information
|
Mutation Site
|
I195M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
A |
|
Country
|
Argentina |
Literature Information
|
PubMed PMID
|
17506609
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2007 |
|
Journal
|
AIDS research and human retroviruses |
|
Title
|
Hepatitis B virus genotype distribution and its lamivudine-resistant mutants in HIV-coinfected patients with chronic and occult hepatitis B. |
|
Author
|
Quarleri J,Moretti F,Bouzas MB,Laufer N,Carrillo MG,Giuliano SF,Pérez H,Cahn P,Salomon H |
|
Evidence
|
The triple mutant rtV173L plus rtL180M plus rtM204V seen in two individuals with genotype A HBV infection causes concomitant amino acid substitutions at positions 164 and 195 (sE164D plus sI195M) in the HBsAg protein as a result of the overlapping reading frames of the envelope and polymerase genes.
|
|
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HBV Mutation Detail Information