|
Mutation Information
|
Mutation Site
|
I195M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Combined Mutation
|
s.I195M+s.E164D |
|
Genotype/Subtype
|
A;D |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Italian |
Literature Information
|
PubMed PMID
|
19475624
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2009 |
|
Journal
|
Journal of medical virology |
|
Title
|
Effect of HIV co-infection on mutation patterns of HBV in patients with lamivudine-resistant chronic hepatitis B. |
|
Author
|
Iacomi F,Vincenti D,Vairo F,Solmone M,Mariano A,Piselli P,Puro V,Capobianchi MR,Antonucci G |
|
Evidence
|
All patients with the triple mutational pattern showed sE164D + sI195M changes in the envelope gene.
|
|
|
HBV Mutation Detail Information